ABSTRACT
Cholesterol granuloma is usually found in chronic middle ear disease. However, it rarely occurs in the sinonasal regions and only a few cases have been reported in the literature. The etiology of the sinonasal cholesterol granuloma is not known yet, and the clinical manifestations are variable. The 78-year-old man complained of facial pain and toothache at first visit. The PNS CT had a homogenous isodense mass occupying right spenoid sinus and extending to right pterygopalatine fossa, infratemporal fossa and masticator space. The PNS MRI had characteristically high signal lesion at both T1- and T2-weighted images. The tumor was completely excised via transantral approach. Pathological confirmation was the cholesterol granuloma with fungal infection consistent with Aspergillus species. This patient is followed up without recurrence.
Subject(s)
Aged , Humans , Aspergillus , Cholesterol , Ear, Middle , Facial Pain , Granuloma , Pterygopalatine Fossa , Recurrence , Sphenoid Sinus , ToothacheABSTRACT
BACKGROUND AND OBJECTIVES: Tinnitus is the conscious experience of sound that originates in the head or neck, and without voluntary origin obvious to that person. The aim of this study was to evaluate the prevalence of dyslipoproteinemias and its correlation with subjective tinnitus in the healthy elderly men (especially in men older than 60 years). SUBJECTS AND METHOD: From January 2007 to January 2008, we randomly selected 150 men at our office visit. Of these men, only 102 complained of subjective tinnitus. All men underwent pure tone audiogram, pitch-match and loudness-balance test for tinnitus, simple X-ray (mastoid series), blood sampling such as total cholesterol, LDL cholesterol, HDL cholesterol, triglyceride and lipoprotein(a) etc, and if necessary, temporal bone imaging study, and vestibular function test. Statistical analyses were performed using the SPSS version 15.0, and the p-value was considered significant when less than 5%. RESULTS: The prevalence of hyperlipoproteinemia had no significant difference between the tinnitus group and the control group. Although there was no correlation between loudness (r=0.008, p>0.05) and pitch (r=0.026, p>0.05) for tinnitus with the serum lipoprotein(a) level, the mean value of serum lipoprotein(a) was significantly different between the two groups (p<0.05). CONCLUSION: The high level of serum lipoprotein(a) may have influence on the subjective tinnitus as a risk or aggravation factor in the healthy elderly men.
Subject(s)
Aged , Humans , Male , Cholesterol , Cholesterol, HDL , Cholesterol, LDL , Dyslipidemias , Head , Hyperlipoproteinemias , Lipoprotein(a) , Lipoproteins , Neck , Office Visits , Prevalence , Temporal Bone , Tinnitus , Vestibular Function TestsABSTRACT
Sialolipoma is a new variant of salivary gland lipoma containing secondary entrapment of acini and ducts of normal salivary gland, first described by Nagao et al. in 2001. We present the clinicopathologic features of two cases, with a review of 18 cases of sialolipoma reported in the literature so far. In our cases, both 59-year-old and 74-year-old men had painless, movable, and soft mass. The finding of neck enhanced computed tomography was a well-demarcated hypodense mass within the superficial lobe of left parotid gland in both cases. So we performed a superficial parotidectomy with preservation of the facial nerve. Grossly, this tumor was a well-demarcating, soft, greasy, yellowish mass, and microscopically, it consisted of mature adipose tissues and normal entrapped glandular epithelium of acini and ducts. This had been recently recognized as a separate entity under the term, "sialolipoma". We report two cases with a review of the literature.
Subject(s)
Aged , Humans , Male , Middle Aged , Epithelium , Facial Nerve , Lipoma , Neck , Parotid Gland , Salivary GlandsABSTRACT
The mucocele of paranasal sinuses is a mucus-filled, epithelial-lined cystic structure resulting from the destruction of the sinus ostia secondary by recurrent inflammation, trauma or intrinsic disease. A 42-year-old man was presented with a left periorbital swelling that developed 7 days ago. CT scan revealed mass lesions with soft tissue density in the left anterior ethmoid and frontal sinus. MRI showed a well- demarcated cystic mass in the left anterior ethmoid sinus with a high signal on both the T1-weighted and T2-weighted images as well as in the left frontal sinus with a low signal on the T1-weighted images and a high signal on the T2- weighted images. The patient subsequently underwent the removal of the left anterior ethmoid and frontal mucocele via a Lynch's approach and a left endoscopic anterior ethmoidectomy. He has no recurrence 6 months after surgery.
Subject(s)
Adult , Humans , Ethmoid Sinus , Frontal Sinus , Inflammation , Mucocele , Paranasal Sinuses , RecurrenceABSTRACT
BACKGROUND AND OBJECTIVES: Recurrent aphthous ulceration (RAU) is most common among benign oral mucosal diseases, but its pathogenesis is not clearly defined yet. We aimed to evaluate the allergic reaction and identify the allergen by using the multiple allergosorbent test (MAST). SUBJECTS AND METHOD: We selected a total of 20 patients with RAU. RAU was not diagnosed by biopsy but by clinical findings, and MAST was performed in all patients. Parameters used were total IgE concentration, type of positive allergens, and the specific IgE concentration. RESULTS: The results were as follows: 1) The total IgE concentration was increased more in the RAU group than in the control group (p<0.05). 2) The type of positive allergens was multiple and had more even distribution in the RAU group than in the control group (p<0.05). 3) The specific IgE concentration according to the positive allergen was higher in the RAU group than in the control group (p<0.05). CONCLUSION: Allergic reactions could be invol-ved in the pathogenesis of RAU. The pathomechanism of allergic reaction to the RAU and the feasibility of treatment options such as avoidance therapy, the immune therapy, and the antihistamine usage need further study.
Subject(s)
Humans , Allergens , Biopsy , Hypersensitivity , Immunoglobulin E , Stomatitis , Stomatitis, AphthousABSTRACT
We present a case of scalp metastasis from papillary thyroid carcinoma which developed on the scalp of a 57-year-old man. The lesion was noticed at the scalp of left parietal area and a biopsy from the nodule showed mostly metastatic papillary form structures with colloidal structure. We performed immunohistochemistry stain using antithyroglobulin antibody, which established the diagnosis of a metastatic lesion from thyroid papillary carcinoma. Total thyroidectomy, excision of scalp nodule, and 131I radiotherapy were performed. No further metastasis has been discovered during the last 12 months.